Month: May 2021

The Right Treatment of gallbladder cancer stage 4

The gallbladder stores part of the bile produced by the liver, which it releases into the gastrointestinal tract later to help digest fats.

Treatment of gallbladder cancer stage 4

However, the gallbladder is not necessary for the digestion process, and the gallbladder afflicts many medical conditions, including cancer, which is a rare type of gallbladder cancer, which is difficult to diagnose.

Stages of gallbladder cancer

The gallbladder consists of 3 different layers, and gallbladder cancer usually begins in the inner layer of it, then cancer cells begin to spread from this layer to the rest of the layers, and if the disease is not diagnosed early, these cancer cells may begin to spread to the rest of the body.

Is gallbladder cancer painful

You may feel abdominal pain that may become increasingly severe and persistent. The pain usually results from a blockage of the bile ducts. The stool color may be pale. People feel tired and upset. And they could feel a lump in their stomachs.

Read more: 8 common questions about gallbladder stones surgery (gallstones)

What is gallbladder cancer stage 4

We have said that gallbladder cancer is rare, but it may affect many people, and what makes it dangerous is that it is difficult to diagnose and that it is not discovered until after advanced stages.

The most difficult stages of gallbladder cancer

Stage 4 gallbladder cancer is the most dangerous stage because it indicates that cancer has moved from the gallbladder to the main blood vessels that drain into the liver, to the lymph nodes, or to other parts of the body, and it is worth noting that people with gallbladder cancer stage 4 live some of them Approximately 5%, that is, 5 people out of every 100 people for a period of five years or more after the discovery of cancer, and the 4th stage is preceded by several stages.

 In the third stage of gallbladder cancer the cancer has spread to the surrounding tissues and lymph nodes, and often doctors cannot remove the cancer cells, Only 10% of the infected people live in this stage, meaning 10 people out of every 100 people, and for a period of 5 years after the diagnosis and discovery of cancer, while in the second stage, 25% and more of people with gallbladder cancer live, and in the first stage of gallbladder cancer, the cancer has moved to Muscles only, and doctors perform some procedures to prevent the cancer from returning to the gallbladder cells, and in most cases 50% of people with gallblader cancer will survive if it is in the first stage.

You should know that choosing the stage of gallbladder cancer is based on scientific foundations, and it is a system established by the American Joint Committee for Cancer Control, and at the beginning of these principles comes the extent of the size of the tumor, i.e. where the cancer cells arrived, and is cancer located on the wall of the gallbladder or moved to neighbor organs In addition to whether or not cancer has spread to the lymph nodes, and whether it has spread to distant organs from the gallbladder or not, and depending on these bases and the results of the examination, the stage of gallbladder cancer is determined.

Read more: Gallbladder Inflammation: symptoms, causes, and treatment

Best hospital for gallbladder cancer treatment

Types of gallbladder cancer

Gallbladder cancer has many types depending on the cells in which cancer develops, and in all cases, the types of gallbladder cancer include the following:

Gallbladder adenocarcinoma:

It is one of the most common types of gallbladder cancer, as it affects nearly 85% of people with gallbladder cancer, and this type begins in the glandular cells in the lining of the gallbladder that produce mucus, and gallbladder glandular cancer has two types as well. The first is a non-papillary adenoma, which is the most common type of gallbladder cancer, and benign papilloma, which affects 6% of gallbladder cancers, and in this type of gallbladder cancer its spread to other organs decreases.

Squamous cell carcinoma:

Squamous cell carcinoma begins from the cells that line the gallbladder, which are cells that resemble skin cells, and squamous cell carcinoma can be adenocarcinoma, which is another type of gallbladder cancer, which is a type that affects the glandular squamous cells.

Read more: The risks of gallbladder surgery during pregnancy

Gallbladder cancer stage 4 symptoms

It is worth noting that the symptoms of gallbladder cancer do not appear except in advanced stages, such as the fourth stage, and these symptoms include the following:

  • Vomiting and nausea.
  • Lose weight.
  • A rise in body temperature.
  • Abdominal distension.
  • The urine becomes dark in color.
  • Abdominal pain, specifically in the upper abdomen.

Jaundice: which is accompanied by yellowing of the eyes and skin when levels of bilirubin rise due to blockage of the bile ducts.

Causes of gallbladder cancer

Doctors have not determined a clear cause of gallbladder cancer, but as is the case in other types of gallbladder cancer, it occurs as a result of a mutation in a person’s DNA, and this mutation leads to abnormal growth in gallbladder cells that cannot be controlled after that, and when the cells that proliferate increase without Controlling it, cancerous tumors form and these cells may move to neighbor organs, and there are many causes of gallbladder cancer and factors that increase the risk of developing it, and these factors include the following:

Stones and cholecystitis:

They are small pieces that form in the gallbladder when the bile contains large amounts of cholesterol, and bilirubin, which is the pigment that appears in the body when red blood cells are broken down, and gallstones cause gallbladder inflammation and blockage in the bile ducts outside the gallbladder or liver. 

The American Society of Clinical Oncology indicate that 90% of people with gallbladder cancer have gallstones, however, it is not necessary for a person with gallstones to develop gallbladder cancer, as 99% of people with gallstones do not develop gallbladder cancer.

Porcelain gallbladder and polyps:

The gallbladder may appear white because its walls have calcified, and this makes it look like porcelain, and the gallbladder can become this way after infection for a chronic period, and polyps are cancerous tumors, but they are small in size and affect 5% of people.

Read more: Gallbladder Operation: Risks, and Cost of Gallbladder stones surgery

People at risk of gallbladder cancer stage 4

This type of gallbladder cancer is four times more common in women than in men, and usually affects people over the age of 65.

Diseases of the biliary tract

The bile ducts affect many conditions, which can lead to the return of bile to the gallbladder and this increases the risk of gallbladder cancer.

Treatment of gallbladder cancer stage 4

The treatment of gallbladder cancer varies depending on the stage the cancer is going through, for example, the doctor resorts to cancer surgery in the early stages of gallbladder cancer in which he removes the gallbladder, or the doctor removes the gallbladder and part of the liver when cancer has moved to some liver cells, and when Gallbladder cancer is small, so the patient does not need other treatments, and only the tumor is removed, and in the fourth stage and other stages, the treatment options include the following:

Gallbladder cancer chemotherapy treatment

Chemical drugs are given through a vein or in the form of pills, to kill fast-growing cancer cells, and the doctor may perform surgery to get rid of cancer cells completely, especially if there is a possibility of their return.

Radiation therapy:

Radiation oncologists use bundles of energy; Like X-rays and protons to eliminate cancer cells, and the doctor can combine radiation therapy with chemotherapy, to completely remove cancer cells.


Medicines are used to stimulate the immune system to eliminate cancer cells, and the doctor may resort to immunotherapy in advanced stages of gallbladder cancer.

Targeted drug therapy:

The doctor gives these drugs, which aim to enter the cancer cells through their weaknesses and then eliminate them, and this treatment option may be the most appropriate for people with gallbladder cancer stage 4.

What is gallbladder cancer stage 4 ?

We have said that gallbladder cancer is rare, but it may affect many people, and what makes it dangerous is that it is difficult to diagnose and that it is not discovered until after advanced stages.

is gallbladder cancer painful?

You may feel abdominal pain that may become increasingly severe and persistent. The pain usually results from a blockage of the bile ducts. The stool color may be pale. People feel tired and upset. And they could feel a lump in their stomachs.

The risks of gallbladder surgery during pregnancy

Perform gallbladder surgery during pregnancy, or any other surgery, although these conditions are uncommon, they do exist. And up to 2% of women need surgery during pregnancy as a result of an organ defect.

The risks of gallbladder surgery during pregnancy

One of the most common operations is gallbladder surgery, in this article, we learn all the details of performing gallbladder surgery during pregnancy.

Read more: 12 drinks that boost gallbladder health

Choosing when to perform gallbladder surgery during pregnancy 

In general, if any surgery can be postponed until the mother gives birth, this is the best option, because in some cases the operations are very urgent, but if you decide to do a dangerous thing such as performing a gallbladder operation during pregnancy, the necessary precautions must be taken, the most important of which is choosing the timing of the operation as follows :

The first trimester of pregnancy:

It is best to avoid any surgery in the first trimester because some risks are resulting from anesthesia and other drugs for the fetus in the first period of its formation, but if the surgery is necessary and cannot be postponed, then there is no escape, whatever the consequences because your health is the most important in this case. 

Read more: The Right Treatment of gallbladder cancer stage 4

The second trimester of pregnancy:

The safest time of pregnancy for surgery, such as gallbladder surgery, if it is not possible to postpone it until after childbirth, in the second trimester the risk of miscarriage is lower and the uterus and fetus are stable, which makes abdominal operations easier for surgeons.

The third trimester of pregnancy:

At this time, the uterus expands to accommodate the growth of the fetus in the prenatal period, so when performing a surgery, there are some precautions that the surgeon takes to avoid the risk of premature labor, or approaching the uterus at this time.

Read more: 8 common questions about gallbladder stones surgery (gallstones)

The risk of gallbladder surgery during pregnancy

In this operation, the surgeon removes the gallbladder through an opening in the abdomen and needs to conduct tests and take some steps before and during the operation that may be dangerous for pregnancy, including:

CT scan:

It is better to rely on an MRI to avoid radiation during pregnancy that can harm the fetus. CT and x-rays are the most dangerous.  


Various research indicates that narcotic drugs are usually safe for the fetus in different pregnancy periods, except for the first trimester, in which it is preferable to avoid the procedure in it if possible to avoid birth defects or any effect on the development of the fetus.

Complications during the operation:

Complications can occur during pregnancy at the time of the operation, so one of the doctors present in the operation must be a gynecologist and obstetrician, especially in the last trimester of pregnancy, in the event of complications, and his presence is important to guide the surgeon and monitor blood pressure and blood pressure in the pregnant woman.

To resort to cesarean delivery:

In the case of an operation and opening the abdomen, it is most likely that a cesarean delivery will be due to the failure of the wound to fully heal in this short period before birth.  

Read more: Gallbladder Inflammation: symptoms, causes, and treatment

Laparoscopic gallbladder surgery

Most of the cholecystectomy operations are now performed laparoscopically, and this makes the existing wound much smaller than before, a very small opening so that only the surgeon can insert the endoscope through it, so do not worry, it is much easier than before.

Finally, postponing gallbladder surgery during pregnancy until after childbirth is the best choice, and so is the case in any other surgery, but if it is not possible to postpone, the health of the mother comes first before anything else, so the final choice is in the hands of the doctor, and if he decides that, You must take all your precautions.

8 common questions about gallbladder stones surgery (gallstones)

Gallstones medical term: is a short term for gallbladder stones. The gallbladder is a small pear-shaped organ located underneath the liver. The gallbladder contains bile, which our body uses to dissolve the fat we eat.
Gallstones is a common condition in middle aged persons and older. By age 65, 20% of women and 10% of men have gallstones.

gallbladder stones surgery Gallstones treatment

Who are at risk? One common codeword is the 4F’s, which means that females up to forty years old, who are frequently fat, and flatulence (a lot of gas) are the ones who develop gallstones, also males and younger people may have gallstones.

Gallstones come in a variety of sizes. They can be small, usually one to two centimeters in diameter. You can have one stone or several stones.

How do gallstones form in the body?

There are several types of gallbladder stones. The most common ones are cholesterol stones (80%), followed by calcium stones (15%), then uric acid stones (5%). Obviously, if your blood cholesterol is high, you are prone to have cholesterol stones. Calcium gallstones may be caused by rapid weight loss or some unclear reason.

Read more: 12 drinks that boost gallbladder health

What are the gallstones symptoms? What are the complications?

Some patients with gallbladder stones do not feel anything and these are just discovered incidentally by an ultrasound scan. These “silent” stones usually require no treatment.
However, if you have symptoms, you could experience abdominal pain, which some describe as colicky (off and on) and radiating to the back. The pain may increase by an intake of a fatty meal, which stimulates the gallbladder to release bile.

Once you develop abdominal pains, then it is best to remove these it by gallbladder stones surgery. Pain relievers may help relieve the pain but they don’t treat them so eventually an operation is needed. If left untreated, complications may occur such as blockage of the stone in the pancreatic duct or common bile duct, or gallbladder inflammation. Once this occurs, an emergency operation is needed.

What are the other diseases may be mistaken for gallstones?

The best test to diagnose gallstones is An ultrasound. However, since organs are located near the gallbladder, several conditions may be causing the abdominal pain. Hence, we should rule out other disorders such as:
Heart disease with chest pains.
Ulcer or heartburn.
Lung problems.
Simple tests such as an chest x-ray and electrocardiogram can help clarify the diagnosis.

Read more: The risks of gallbladder surgery during pregnancy

How are gallstones treated? What is a lap-chole or a laparoscopic gallbladder stones surgery?

If there are no big gallstones symptoms, most doctors would not advise surgery. Just be careful with your diet and watch. However, if there are episodes of pain in your abdominal, then gallstones are best removed surgically.

What is Cholecystectomy:

This term used to describe the surgical procedure of removing the gallbladder. Usually, the surgeon makes a small opening in the abdomen to remove the gallbladder. Hence we call this procedure as the Open-Cholecystectomy.

There is a newer surgical technique now that just makes a few punctures and removes the gallbladder using video-guided equipments. This is called laparoscopic gallbladder stones surgery. The advantage of this technique is that it leaves no scar in the abdomen and the patient recovers more quickly. Ask your doctor about these options.

Read more: The Right Treatment of gallbladder cancer stage 4

Are there drugs that can dissolve gallstones?

Many people are afraid of gallbladder stones surgery and they try to look for medical means to get rid of the stones. Unfortunately, none of these medications or food items are reliable in removing the stones in your gallbladder.
Some drugs have been used to treat stones, such as ursodeoxycholic acids. These drugs are taken for up to 2 years, and there is no guarantee that they would treat stones.

What about alternative medicine? Are there natural foods that can dissolve gallstones?

The answer is “no.” There is no truth to the so-called “gallbladder flush.” Despite the internet popularity of so-called remedies such as Mint, lemon juice and olive oil, there is no evidence that it works. I have talked with many doctors who say that despite these remedies, their patients will come back with the same number of gallbladder stones. In some cases, the stones actually got bigger and increased in number in your gallbladder. Thus, do not rely on these remedies. See your doctor for the correct treatment.

How do you prevent gallstones?

There are no surefire ways to prevent gallstones, but the advices below are our best bets.

Eat a low fat diet and high fiber:

A gallstones diet rich in vegetables and fruits may help prevent more gallstones from forming. Choose fish instead of meat products.

Maintaining an ideal body weight:

Obesity increases the risk of developing gallbladder stones.

Lose excess weight but do it gradually:

Employing a crash diet and losing several pounds for your body quickly may actually cause gallbladder stones.
This is because when the body fat is mobilized too quickly, this can cause cholesterol stones in yours.
So, lose weight safely, by around 1 to 2 pounds only per week this is the best gallbladder diet.

Start exercising regularly:

Exercise and walking can help maintain a healthy and active digestive system.

This is the Top queries I found, if you have any question please put it in comments. Good luck.